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全身性红斑性狼疮(systemic lupus erythematosus)之病人,约有50—80％会有肾脏病徵状,活体肾穿刺组织之显微观察,是最可靠且敏感之检查方法,可以提供临床医师治疗之参考。长庚医院在两年当中,有319例肾穿刺标本,其中25例为狼疮性肾炎(Lupus nephritis),此25例在临床上均符合美国风湿病学会(American Rheumatism Association)所订之标准。穿刺所得之标本均分为三部分,作普通光学显微,萤光显微及电子超显微检查,依据联合国卫生组织(WHO)所订之肾小球组织变化分类如下表:
About 50-80% of patients with systemic lupus erythematosus have kidney disease symptoms. Microscopic observation of living renal biopsy tissue is the most reliable and sensitive method of examination and may provide a reference for clinicians . Chang Gung Memorial Hospital in the two years, there are 319 cases of renal biopsy specimens, of which 25 cases of Lupus nephritis, these 25 cases clinically meet the American Rheumatism Association (American Rheumatism Association) set the standard. Puncture the resulting specimens are divided into three parts for ordinary optical microscopy, fluorescence microscopy and electron microscopic examination, according to the United Nations Organization for Health (WHO) classification of glomerular changes in the table below: