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本文报告了用马来丝虫成虫冰冻切片抗原作 IFAT 检测班氏丝虫微丝蚴血症者抗体阳性率为88.89％;非流行区健康居民抗体阳性率为3.92％。基本消灭丝虫病后8年的地区原微丝蚴血症者和阴性居民抗体阳性率分别为13.54％和10.84％;基本消灭后15年原微丝蚴血症者和阴性居民抗体阳性率分别为6.45％和5.16％;基本消灭后24年原微丝蚴血症者和阴性居民抗体阳性率分别为3.67％和3.96％。基本消灭丝虫病后15年的地区人群抗体阳性率已降到非流行区健康人群水平(X~2=0.48 P>0.05)。因此认为 IFAT 可作为我省丝虫病防治后期和基本消灭丝虫病后流行病学监测的主要方法之一。此外,观察到微丝蚴血症者血清抗体阳性率和阳性 GMRT 与微丝蚴密度无相关性。
In this paper, the positive rate of antibodies against microfilariae of Bancroft filariasis was 88.89% using frozen section antigen of adult Malayan worm as IFAT. The positive rate of healthy resident antibody in non-endemic area was 3.92%. The positive rate of antibody of the original microfilaremia and negative residents in the area of 8 years after the basic elimination of filariasis were 13.54% and 10.84%, respectively. The positive rates of antibody of the original microfilaremia and negative residents after 15 years basically eliminated Were 6.45% and 5.16%, respectively. The positive rates of antimicrobial antibodies and negative residents 24 months after the basic elimination were 3.67% and 3.96% respectively. The positive rate of antibody in local population after 15 years of basic elimination of filariasis has dropped to healthy population level in non-endemic areas (X ~ 2 = 0.48 P> 0.05). So IFAT can be regarded as one of the main methods for epidemiological surveillance of filariasis after the latter period of filariasis prevention and control in our province. In addition, there was no correlation between the positive rate of serum antibody and the positive GMRT and the microfilariae density in microfilaremia.