论文部分内容阅读
目的:分析综合干预对普外科合理使用抗菌药物的作用。方法:选取医院2012年4月—2014年5月间普外科手术患者168例,将其分为对照组(80例)和观察组(88例);对照组患者给予常规方法,管理抗菌药物使用的患者,观察组患者给予综合干预抗菌药物的使用,比较两组患者一般资料、用药时间、用药量、创口感染率、不良反应发生率及用药不合理率等。结果:观察组患者用药不合理率为20.45%显著低于对照组为35.00%(P<0.05);观察组患者感染发病率为13.64%略低于对照组为13.75%(P>0.05)。结论:综合干预措施应用于普外科抗菌药物使用管理中,其在控制创口感染的基础上能降低不良反应发生率及不合理用药率。
Objective: To analyze the effect of comprehensive intervention on the rational use of antibacterials in general surgery. Methods: A total of 168 patients undergoing general surgery from April 2012 to May 2014 were selected and divided into control group (80 cases) and observation group (88 cases). Patients in control group were given conventional methods to manage the use of antimicrobial agents Of the patients in the observation group were given the comprehensive intervention of antibacterial drugs, comparing the two groups of patients general information, medication time, dosage, wound infection rate, the incidence of adverse reactions and medication unreasonable rate. Results: The irrational rate of medication in observation group was significantly lower than that in control group (20.45% vs 35.00%, P <0.05). The incidence of infection in observation group was 13.64%, which was slightly lower than that of control group (13.75%, P> 0.05). Conclusion: The comprehensive interventions are used in the management of general surgery antibiotics, which can reduce the incidence of adverse reactions and irrational drug use based on the control of wound infections.