论文部分内容阅读
利用录象脑电图加强监测，￣（９９ｍ）Ｔｃ－ＨＭＰＡＯ－ＳＰＥＣＴ，￣（１２３）Ｊ－Ｉｏｍａｚｅｎｉｌ－ＳＰＥＣＴ、ＭＲＩ对４０例局限性癫痛患者进行研究。分析发作期及发作间歇期Ｖｉｄｅｏ／ＥＥＧ的结果：３８例（８２％）表现局限性癫痛样活动，￣（９９ｍ）ＴＣ－ＨＭＰＡＯ－ＳＰＥＣＴ局部脑血流异常２１例（５２％），￣（１２３）Ｊ－Ｉｏｍａｚｅｎｉｌ－ＳＰＥＣＴ局部脑苯二氮革受体密度减低２５例（６３％），ＭＲＩ结构异常１８例（４５％）。Ｉｏｍａｚｅｎｉｌ对癫痈灶定位比ＨＭＰＡＯ敏感，有较高诊断价值。这些神经影像技术可显示病灶内结构和功能改变。对癫痈发作提供了神经病理学基础，是对癫痛定位非创伤性的有效检查方法。
Surveillance was performed using video-electroencephalography (EEG) in 40 patients with localized epilepsy under ~ (99m) Tc-HMPAO-SPECT and ~ (123) J-Iomazenil-SPECT. Video / EEG results from the onset and interictal episodes were analyzed: 38 (82%) exhibited localized epilepsy-like activity, ~ (99m) TC-HMPAO-SPECT had local cerebral blood flow abnormalities in 21 123) J-Iomazenil-SPECT local brain benzodiazepine receptor density decreased in 25 cases (63%), MRI structure abnormalities in 18 cases (45%). Iomazenil is more sensitive to epilepsy than HMPAO and has higher diagnostic value. These neuroimaging techniques can show structural and functional changes in the lesion. It provides a neuropathological basis for the onset of epilepsy and is a non-invasive and effective method of detecting epilepsy.