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目的：探讨快速静脉滴注硝普钠（ＳｏｄｉｕｍＮｉｔｒｏｐｒｕｓｓｉｄｅ，ＳＮＰ）和甘露醇（Ｍａｎｎｉｔｏｌ）治疗脑水肿并发肺水肿的疗效。方法：对１５例患者在心电监护下给予ＳＮＰ５０ｍｇ加入１０％葡萄５００ｍＬ静滴，剂量从３００μｇ／ｍｉｎ开始，根据血压调整逐渐减量；１５ｍｉｎ后给予２０％Ｍａｎｎｉｔｏｌ１２５～２５０ｍＬ静滴，２ｈ后重复Ｍａｎｎｉｔｏｌ剂量。结果：临床总有效率７３．３％，治疗后ＨＲ、ＢＰ明显降低（Ｐ＜０．００１），ＰａＯ２、ＳａＯ２明显升高（Ｐ＜０．００１）。结论：快速静滴ＳＮＰ和Ｍａｎｎｉｔｏｌ对抢救脑水肿并发肺水肿有较好的疗效
Objective: To investigate the curative effect of rapid intravenous infusion of sodium nitroprusside (SNP) and mannitol on cerebral edema complicated with pulmonary edema. Methods: Fifteen patients were given SNP50mg intravenously with 50% intravenous infusion of 10% grapevine under electrocardiographic monitoring. The dose was 300μg / min. The dose was gradually reduced according to the blood pressure. After 15min, 20% Mannitol was given as 125-250mL intravenous drip. After 2h, Mannitol dose . Results: The total clinical effective rate was 73.3%. After treatment, HR and BP were significantly decreased (P <0.001) and PaO2 and SaO2 were significantly increased (P <0.001). Conclusions: Rapid intravenous infusion of SNP and Mannitol are effective in treating cerebral edema and pulmonary edema