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采用放射配体结合法测定人白细胞糖皮质激素受体(GCR),ANAE法检查T淋巴细胞。102例放射工作者和8例慢性放射病患者的T淋巴细胞率分别为67.30±1.19％和41.30±1.23％,显著低于101例正常人值78.14±1.11％(P<0.001)。作者还测定了17例待诊和确诊慢性放射病病人的GCR,6例呈正常人的周日节律,早晨高,晚上低(P<0.01),其中1例为放射病人,其余11例的GCR周日节律明显颠倒,晨低晚高(P<0.01),其中7例为确诊的慢性放射病。并讨论了这些指标对慢性放射病的诊断意义。
Human leukocyte glucocorticoid receptor (GCR) was measured by radioligand binding assay and T lymphocytes were examined by ANAE assay. The T lymphocyte rates of 102 radiologists and 8 chronic radiotherapy patients were 67.30 ± 1.19% and 41.30 ± 1.23%, respectively, which were significantly lower than those of 101 normal subjects (78.14 ± 1.11%, P <0.001). The authors also measured GCR in 17 patients with diagnosed and diagnosed chronic radiation sickness, 6 patients with normal circadian rhythm, high morning and evening low (P <0.01), of whom 1 was radiation and the other 11 were GCR weeks Day rhythm was significantly reversed, morning and evening high (P <0.01), of which 7 cases were diagnosed as chronic radiation sickness. And discuss the diagnostic significance of these indexes to chronic radiation sickness.