Synthesis of optically active polymers bearing amino acid moieties by atom transfer radical polymeri

• 出 处: Chinese Chemical Letters
• 发表日期: 2007年07期
• 关键词: polymerization optically ATRP initiating rotation polyacrylamide leucine narrow

We report here an approach toward the synthesis of optically active polyacrylamide bearing amino acid moieties, poly[N- methacryloyl L-leucine methyl ester] (PMALM), with controlled average number molecular weight (Mn) and relatively narrow polydispersity index (PDI, Mw/Mn < 1.3) by atom transfer radical polymerization (ATRP) using initiating system methyl 2- bromopropionate/CuBr/tris(2-dimethylaminoethyl) amine. The optical properties of the resulting polymers were evaluated fromspecific optical rotation value and CD spectra.

We report here an approach toward the synthesis of optically active polyacrylamide bearing amino acid moieties, poly [N-methacryloyl L-leucine methyl ester] (PMALM) with controlled average number molecular weight (Mn) and relatively narrow polydispersity index / Mn <1.3) by atom transfer radical polymerization (ATRP) using initiating system methyl 2-bromopropionate / CuBr / tris (2-dimethylaminoethyl) amine. The optical properties of the resulting polymers were evaluated from specific optical rotation value and CD spectra.