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目的:为深入开展抗菌药临床应用专项整治活动(简称专项活动)、促进抗菌药的合理应用提供参考。方法:调查广西某市10家二级医院,通过查阅资料、抽查处方和病历,计算抗菌药使用强度、各种控制指标等,评价专项活动开展情况及效果。结果:10家医院均能按要求开展专项活动,落实合理用药第一责任人,明确控制指标、签订责任状,落实抗菌药分级管理制度,开展处方点评,品规选择符合规定;急诊、住院患者抗菌药使用率基本达标,但门诊抗菌药使用率及清洁手术预防用药率高、品种选择不恰当、疗程长等不合理现象仍普遍存在。结论:各医疗单位通过开展专项活动,部分管理指标趋于好转,但各单位对不合理用药的干预措施及力度不一,效果差异较大。各医院仍需加大整治力度,加大对不合理用药干预力度,以提高抗菌药临床合理应用水平。
OBJECTIVE: To provide a reference for carrying out the special rectification activities (referred to as special activities) for the clinical application of antibacterials and promoting the rational application of antibacterials. Methods: To investigate the secondary hospitals in a certain city of Guangxi and evaluate the use of antimicrobial agents and various control indexes by referring to the data, random sampling and medical records, and evaluating the performance and effectiveness of special activities. Results: All the 10 hospitals were able to carry out special activities according to the requirements, implement the first responsible person for rational drug use, clearly control the indicators, sign the responsibility status, implement the antimicrobial drug classification management system, carry out prescription reviews, Antibacterial drug utilization rate basically reached the standard, but outpatient antibacterial drug usage rate and clean operation prevention drug rate is high, the product variety is not appropriate, long course of treatment and other unreasonable phenomena are still ubiquitous. Conclusion: Through the implementation of special activities, some medical management units tend to improve some of their management indicators. However, the interventions and efforts made by various units on irrational drug use vary with different effects. The hospitals still need to step up efforts to rectify and intensify efforts to intervene in irrational drug use in order to improve the clinical application of antimicrobial agents.