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目的:分析阴道镜活检联合宫颈锥切在宫颈癌筛查中的价值。方法:选取我院2014年4月至2015年7月中收治的54例宫颈(上皮内)癌变患者作为本次实验的研究对象,对所有患者均采取阴道镜活检以及宫颈锥切的联合诊断,手术结束后,再将其病理标本进行相应的检查,对其阴性预测值、阳性预测值以及灵敏度与特异性进行比较。结果:诊断结束后,阴道镜检查显示:20例(37.04%)患者为CINⅠ级,18例(33.33%)患者为CINⅡ级,14例(25.93%)患者为CINⅢ级;宫颈锥切术显示:18例患者为CINⅠ级,16例患者为CINⅡ级,13例患者为CINⅢ级,5例浸润癌,其诊断真阳性为47例,假阳性为7例,灵敏度为94.42%,特异度为93.48%,阳性预测值为94.58%,阴性预测值为36.59%。54例接受阴道镜检查的47例患者的病情与其宫颈锥切术病理检查的结果相同,其中5例浸润癌漏诊,准确率为87.04%。结论:阴道镜活检联合宫颈锥切在宫颈癌筛查中的价值比较明显,可显著提高其诊断的准确率,具有广泛推广的价值。
Objective: To analyze the value of colposcopy biopsy and cervical conization in cervical cancer screening. Methods: Fifty-four patients with cervical (intraepithelial) carcinoma who were treated in our hospital from April 2014 to July 2015 were selected as the subjects of this study. All patients underwent colposcopy biopsy and conization of cervical conization, After surgery, and then the pathological specimens were checked accordingly, its negative predictive value, positive predictive value and sensitivity and specificity were compared. Results: After diagnosis, colposcopy showed that CIN Ⅰ level was found in 20 cases (37.04%), CIN Ⅱ level in 18 cases (33.33%), and CIN Ⅲ level in 14 cases (25.93%). Cervical conization showed that: 18 patients were CIN Ⅰ grade, 16 patients were CIN Ⅱ grade, 13 patients were CIN Ⅲ grade, 5 cases of invasive carcinoma, the diagnosis of true positive was 47 cases, false positive was 7 cases, the sensitivity was 94.42% and the specificity was 93.48% , The positive predictive value was 94.58%, the negative predictive value was 36.59%. Forty-four patients undergoing colposcopy were diagnosed as having the same pathological findings as cervical conization, including 5 missed diagnosis of invasive carcinoma with an accuracy rate of 87.04%. Conclusion: The value of colposcopy biopsy combined with cervical conization in the screening of cervical cancer is more obvious, which can significantly improve the diagnostic accuracy and has the value of wide promotion.