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The effect of sterilization methods on biological activity of fibronectin on the surface of biomaterials was elaborated in the present study.Sterile protein-modified biomaterials were fabricated by microfilter filtration and UV irradiation,respectively.UV irradiation altered the conformation of surface-adsorbed fibronectin and further affected the attachment,morphology and biological function of endothelial cells.However,
The effect of sterilization methods on biological activity of fibronectin on the surface of biomaterials was elaborated in the present study. Sterile protein-modified biomaterials were fabricated by microfilter filtration and UV irradiation, respectively. UV irradiation altered the conformation of surface-adsorbed fibronectin and further affected the attachment, morphology and biological function of endothelial cells. However,