论文部分内容阅读
目的:应用交感神经皮肤反应(SSR)检查了解椎基底动脉供血不足性眩晕(VBI)患者交感神经反射活动,并探讨SSR对VBI的诊断价值。方法:对56例VBI患者在急性发作期及恢复期行SSR检查,并与56例健康人作对照。结果:VBI组急性发作期SSR潜伏期(Lat)、波幅(Amp)上肢分别为(1.53±0.35)s,(2.34±1.00)mV;下肢分别为(2.07±0.38)s,(1.21±0.55)mV。恢复期Lat,Amp上肢分别为(1.40±0.20)s,(2.82±1.00)mV;下肢分别为(1.81±0.22)s,(1.74±0.77)mV。正常对照组Lat,Amp上肢分别为(1.35±0.14)s,(2.90±1.29)mV;下肢为(1.78±0.16)s,(1.78±0.80)mV。VBI组急性发作期SSRLat及Amp较正常对照组差异均有显著性意义(q=4.48～7.99,P<0.01),SSR总异常率为66%(37/56)。恢复期Lat和Amp较正常对照组差异无显著性意义(P>0.05),但SSR异常率为9%(5/56)。结论:VBI患者可出现交感神经功能暂时性损害,病情控制后交感神经功能可随之改善,SSR检查可作为VBI诊断的参考指标。
Objective: To investigate the sympathetic reflex activity in patients with vertebrobasilar insufficiency vertigo (VBI) by using sympathetic skin reaction (SSR) and to explore the value of SSR in the diagnosis of VBI. Methods: Fifty-six VBI patients underwent SSR during acute exacerbation and recovery and compared with 56 healthy controls. Results: In the VBI group, the SSR latency (Lat) and amplitude (Amp) were (1.53 ± 0.35) s and (2.34 ± 1.00) mV in the acute exacerbation episode and 2.07 ± 0.38 and 1.21 ± 0.55 . During the recovery period, the upper limbs were (1.40 ± 0.20) s and (2.82 ± 1.00) mV, while the lower limbs were (1.81 ± 0.22) s and (1.74 ± 0.77) mV, respectively. In normal control group, the upper extremities of Lat and Amp were (1.35 ± 0.14) s and (2.90 ± 1.29) mV respectively; while the lower limbs were (1.78 ± 0.16) s and (1.78 ± 0.80) mV respectively. The SSRLat and Amp in acute episode of VBI group were significantly different from those of normal control group (q = 4.48-7.99, P <0.01). The total SSR rate was 66% (37/56) in VBI group. There was no significant difference between Lat and Amp during recovery (P> 0.05), but the abnormal rate of SSR was 9% (5/56). CONCLUSIONS: Temporary damage to sympathetic function may occur in patients with VBI. Sympathetic nerve function may be improved after disease control. SSR may be used as a reference for diagnosis of VBI.