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评价硫酸镁对不适合溶栓治疗的急性心梗(AMI)患者的治疗效果。 方法 试验采用前瞻性、随机、双盲和安慰剂对照方式。病例来源于1990年至1993年因不适合溶栓而住入重症冠心监护病房的215例AMI,剔除不合标准者后治疗组96例(静滴硫酸镁)和对照98例(静滴等渗葡萄糖)。治疗组第一个48小时接受硫酸镁22g(91.6mmol)(第一个3小时静滴6g,在随后的21
To evaluate the therapeutic effect of magnesium sulfate on patients with acute myocardial infarction (AMI) who are unsuitable for thrombolytic therapy. METHODS: A prospective, randomized, double-blind, and placebo-controlled trial was used. The cases were from 215 AMI patients admitted to the intensive care unit from 1990 to 1993 who were unsuited for thrombolysis. The patients in the treatment group were treated with intravenous infusion of 96 cases (intravenous infusion of magnesium sulfate) and 98 cases of untreated patients glucose). The treatment group received 22 g (91.6 mmol) of magnesium sulfate for the first 48 hours (6 g intravenously for the first 3 hours followed by 21