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复方乳酸钠注射液是小儿液体疗法的常用制剂,根据临床需要有多种配方,我院常用的有含钾3:2:1液、10%葡萄糖2:1液、10%葡萄糖改良达鲁氏液等。其中主要含有葡萄糖、乳酸钠、氯化钠等。过去我院配制这类注射液是按下述1法配制。在二十年的使用过程中,虽在临床上未发现有任何副作用,但在制剂质量上还存在一定的问题,如灭菌后颜色变黄、葡萄糖含量下降、放置较久产生沉淀。为了提高本品质量,对其配制方法进行了实验。
Compound sodium lactate injection is commonly used in pediatric liquid therapy, according to the clinical needs of a variety of formulations, our hospital commonly used potassium 3: 2: 1 solution, 10% glucose 2: 1 solution, 10% glucose modified Daruss solution Wait. Which mainly contains glucose, sodium lactate, sodium chloride and so on. In the past, our hospital prepared such injection is formulated according to the following 1 method. In the course of two decades of use, although no side effects have been found clinically, there are still some problems in preparation quality. For example, after the sterilization, the color turns yellow, the glucose content drops and the precipitate settles for a long time. In order to improve the quality of this product, its preparation methods were tested.