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目的 探讨低浓度ＨＢｓＡｇ感染者血清学乙肝标志物的表现模式以揭示其流行病学特征。方法 采用ＥＩＪＳＡ法对 日常工作中的血清标本进行筛选，共收集到２５２份低浓度和３８７份高浓度ＨＢｓＡｇ血清标本：并经ＭＥＩＡ确证后采用ＥＬＩＳＡ 法对其六项血清学乙肝标志物进行检测；为表述方便，设定血清学乙肝标志物检测项目第１～５项的排列顺序分别为ＨＢｓＡｇ、 Ａｎｔｉ－ＨＢｓ、ＨＢｅＡｇ、Ａｎｔｉ－ＨＢｅ、Ａｎｔｉ－ＨＢｃ－ＩｇＧ，并以出现阳性项目的序号为该模式的代码。结果低浓度ＨＢｓＡｇ感染者在人群 中的比例近０．７％，占所有ＨＢｓＡｇ阳性感染者的６．８６％；低浓度和高浓度组血清学乙肝标志物的表现模式分别有１０种和７ 种，各模式在两组间的检出率不完全相同（１３５、１４５、１３４５，Ｐ＜０．０５；１３、１５、１２３５、１２３４５，Ｐ＞（０．０５），且两组间各模式的Ａｎｔｉ－ＨＢｃ－ ＩｇＭ检出率亦不尽相同（１３５、１４５，Ｐ＜０．０５： １５、１２３５、１３４５，Ｐ＞０．０５），但两组各模式均以１４５模式为最高（６.８％和５５．０％），其次为 １３５和１５模式（分别为１６．７％、２８．２％和
Objective To explore the serological markers of hepatitis B in low-concentration HBsAg-infected patients to reveal its epidemiological characteristics. Methods Serum samples from routine work were screened by EIJSA method. A total of 252 low-concentration and 387 high-concentration HBsAg serum samples were collected and validated by MEIA. Six serological markers of hepatitis B were detected by ELISA. For the convenience of expression, the sequence of the first to fifth serological markers of hepatitis B were set as HBsAg, Anti-HBs, HBeAg, Anti-HBe and Anti-HBc-IgG, Pattern of the code. Results The proportion of low-concentration HBsAg-infected persons in the population was nearly 0.7%, accounting for 6.86% of all HBsAg-positive patients. The serological markers of hepatitis B in low and high concentration groups were 10 and 7 The detection rates of the two groups were not all the same (135,145,1345, P <0.05; 13,15,125,12345, P> 0.05) The detection rates of Anti-HBc-IgM were also different (135,145, P <0.05: 15,1235,1345, P> 0.05). 8% and 55.0%), followed by 135 and 15 patterns (16.7%, 28.2%, respectively)