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目的探讨桥脑出血继发肥大性下橄榄核变性(HOD)的MRI表现。方法回顾性分析12例桥脑出血后继发HOD的MRI表现,12例均行MRI常规序列和扩散加权成像(DWI)、磁敏感加权成像(SWI)或梯度回波(T2*WI)序列扫描,2例行扩散张量成像(DTI)扫描。结果 MRI表现为同侧或双侧下橄榄核体积增大或无明显变化,T1WI呈等或稍低信号,T2WI呈稍高或高信号,液体衰减反转恢复序列(FLAIR)呈等或稍高信号,DWI呈等或稍高信号,ADC图呈等或稍高信号,SWI或T2*WI呈等或稍高信号,其对原发出血病灶显示最好,DTI示病变侧纤维束稀少,3例并发双侧桥臂变性。结论 HOD多继发于桥脑背盖部出血,有特定的发病部位和较为特征的MRI表现,结合其原发病变可对HOD作出正确诊断。
Objective To investigate the MRI findings of hypertrophic olivary nucleus degeneration (HOD) secondary to pontine hemorrhage. Methods The MRI findings of 12 patients with secondary HOD after pontine hemorrhage were retrospectively analyzed. All 12 patients underwent MRI scan with diffusion weighted imaging (DWI), magnetic resonance weighted imaging (SWI) or gradient echocardiography (T2 * WI) 2 routine diffusion tensor imaging (DTI) scan. Results The MRI showed that the volume of olivary nucleus increased or not under the same side or bilateral, T1WI showed equal or slightly lower signal, T2WI showed slightly higher or higher signal, FLAIR was equal or slightly higher DWI was equal or slightly higher signal, ADC showed equal or slightly higher signal, SWI or T2 * WI was equal or slightly higher signal, which showed the best primary hemorrhagic lesions, DTI lesions showed thin side of the fiber bundle, 3 Case complicated bilateral bridge degeneration. Conclusion HOD mostly has secondary hemorrhage in the dorsal lid of the pons. It has a specific site of attack and a more characteristic MRI manifestations. Combined with its primary lesion, HOD can be correctly diagnosed.