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腺苷(Adenosine)具有冠脉扩张作用,尚能抑制窦房结和房室结活性,减弱心房收缩,减弱儿茶酚胺的心室肌兴奋作用,以及抑制心室自律性。心脏的腺苷受体细胞膜外表面有两种不同的嘌呤受体(Purinoceptors),即P_1和P_2受体。细胞溶解产物中的腺苷,与P部位相结合,改变嘌呤环,从而抑制腺苷酸环化酶;与细胞外表面的R部位相结合,则改变核糖环。R部位受体,
Adenosine has coronary dilation effect, still can inhibit the activity of the sinus node and atrioventricular node, reduce atrial contraction, reduce the excitatory effect of catecholamines ventricular muscle, and inhibit ventricular self-regulation. There are two different purinoceptors on the outer surface of the cardiac adenosine receptor cell membrane, the P 1 and P 2 receptors. Adenosine in cell lysate, combined with the P site, to change the purine ring, thereby inhibiting adenylate cyclase; combined with the R site on the outer surface of the cell, then change the ribose ring. R site receptor,