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目的研究经皮穴位电刺激镇痛在卵泡数≤5的卵巢低反应患者经阴道超声引导下穿刺取卵术中的应用,探讨经皮穴位电刺激的镇痛效果和安全性。方法将80例卵泡数≤5的卵巢低反应患者按随机数字法分为2组,对照组在术前30分钟给予Mock TEAS仪,观察组给予TEAS仪;观察各组患者取卵术前紧张、焦虑、恐惧等应激水平,取卵术后即刻与1h后疼痛评分,获卵数及生化妊娠率。结果观察组在术后即刻及术后1小时疼痛评分均与对照组没有显著差异(P>0.05);获卵数、生化妊娠率在观察组与对照组间差异未见统计学意义(P>0.05)。穿刺卵泡数≤2的观察组患者术前紧张水平和术后即刻疼痛评分均高于对照组,组间差异具有统计学意义(P<0.05);焦虑、恐惧水平和术后1h疼痛评分两组间差异未见统计学意义(P>0.05)。穿刺卵泡数≥3且≤5的观察组患者术前紧张、焦虑、恐惧等应急水平和术后即刻及术后1h疼痛评分组间差异均未见统计学意义(P>0.05)。结论经皮穴位电刺激镇痛对于卵泡数≤5的卵巢低反应患者的获卵数及生化妊娠率均没有不良影响,但其镇痛效果尚需进一步探讨。
Objective To study the application of transcutaneous electroacupuncture (EAE) analgesia in transvaginal ultrasound-guided ovarian aspiration in patients with ovarian hypofunction less than 5 follicles to explore the analgesic effect and safety of transcutaneous acupoint electrical stimulation. Methods Eighty ovarian hyporesponses with ≤5 follicles were randomly divided into two groups according to random number method. The control group was given Mock TEAS instrument 30 minutes before operation and the TEAS instrument was given to the observation group. The preoperative ovulation, Anxiety, fear and other stress levels, immediately after ovulation and 1h after the pain score, number of oocytes and biochemical pregnancy rate. Results The pain scores of the observation group immediately after operation and 1 hour after operation were not significantly different from those of the control group (P> 0.05). The number of oocytes and the rate of biochemical pregnancy in the observation group and the control group showed no significant difference (P> 0.05). The preoperative tense level and immediate postoperative pain score in the observation group with the number of follicles less than 2 were significantly higher than those in the control group (P <0.05). There were significant differences in anxiety, fear level and postoperative 1h pain score The difference was not statistically significant (P> 0.05). There were no statistically significant differences in the levels of preoperative stress, anxiety, fear and other emergency levels between the observation group of puncture follicles ≥3 and ≤5, and the pain scores immediately after operation and 1h after operation (P> 0.05). Conclusion Transcutaneous acupoint electrical stimulation of analgesia has no adverse effect on the number of oocytes retrieved and the rate of biochemical pregnancy rate in patients with ovarian hypofunction less than 5 follicles, but its analgesic effect needs further study.