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Context: While several models have been developed to predict mortality following intracerebral hemorrhage (ICH), the functional outcome and its predictors in surviving patients have been poorly investigated so far. Objectives: To identify predictors and validate a prognostic model for independent functional outcome in patients with acute ICH. Design: An inception cohort was assessed on the National Institutes of Health Stroke Scale (NIH-SS) at admission and followed-up after 100 days. Setting: 11 neurological departments with an acute stroke unit. Patients: 207 consecutive patients who were neither comatose nor intubated at admission within 6 hours after ICH and with complete follow-up. Results: After 100 days, 40 patients (19.3 %) had died, 78 (37.7%) had regained functional independence (Barthel Index ≥95) and 89 (43%) had survived but not recovered. In these patients, age and the NIH-SS total score were identified as independent predictors for functional independence after 100 days. With the predefined cut-off value, the prognosis of 79.8%of all patients could be predicted accurately upon validation in an independent data set of 173 non-comatose patients with acute ICH. Conclusion: Our study provides a validated prognostic model for prediction of complete recovery following ICH which could be very useful for the design of clinical studies.
Context: While several models have been to predictors of following intracerebral hemorrhage (ICH), the functional outcome and its predictors in surviving patients have been poorly investigated so far. Objectives: To identify predictors and validate a prognostic model for independent functional outcome in patients with acute ICH. Design: An inception cohort was assessed on the National Institutes of Health Stroke Scale (NIH-SS) after admission and followed-up after 100 days. Settings: 11 neurological departments with an acute stroke unit. Patients: 207 consecutive patients who were neither comatose nor intubated at admission within 6 hours after ICH and with complete follow-up. Results: After 100 days, 40 patients (19.3%) had died, 78 (37.7%) had regained functional independence (Barthel Index ≥95) and 89 (43%) had survived but not recovered. In these patients, age and the NIH-SS total score were identified as independent predictors for functional independence after 100 days With the predefined cut-off value, the prognosis of 79.8% of all patients could be predicted accurately upon validation in an independent data set of 173 non-comatose patients with acute ICH. Conclusion: Our study provides a validated prognostic model for prediction of complete recovery following ICH which could be very useful for the design of clinical studies.