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目的探讨抗凝治疗的的妇科围手术时应用抗凝药物的方法及其安全性分析。方法回顾分析2005年~2013年61例在抗凝治疗时需要进行妇科手术的女性患者的临床资料,将其列为研究组,随机选取61例无抗凝治疗的需要妇科手术的患者作为对照组。对比两组的围手术期的凝血功能和手术出血情况。结果研究组入院时的PT17.2±2.8,INR1.7±0.5,对照组入院时的PT12.8±1.1,INR1.21±0.3,两组比较有差异(P<0.05)。手术出血研究组的403±98ml,对照组354±40ml,两组比较无差异高(P>0.05)。结论围手术期严格按照抗凝药物的半衰期进行停药,对抗凝治疗的患者进行妇科手术是安全的。
Objective To investigate the anticoagulant anticoagulant therapy in gynecological perioperative methods and safety analysis. Methods The clinical data of 61 female patients undergoing gynecological surgery during the anticoagulation period from 2005 to 2013 were retrospectively analyzed. They were included in the study group, and 61 patients without gynecological surgery were randomly selected as the control group . Perioperative coagulation and surgical bleeding were compared between the two groups. Results The PT17.2 ± 2.8, INR1.7 ± 0.5 at admission, PT12.8 ± 1.1 and INR1.21 ± 0.3 at admission in the study group were significantly different between the two groups (P <0.05). There were no significant differences between the two groups (P> 0.05). Conclusions Perioperative period is strictly in accordance with the half-life of anticoagulant drug withdrawal, the anticoagulant treatment of patients with gynecological surgery is safe.