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首先问世的脊髓灰质炎死疫苗(脊灰死疫苗),在50年代免疫效果不佳,嗣后经过大量研究,于1977年研制成1种高效的无感染性脊灰死疫苗。本文叙述了该疫苗免疫后产生的循环抗体、免疫记忆与对麻痹型脊髓灰质炎长期免疫力之间的关系。
The first polio vaccine (poliovirus) that died of the first outbreak of immunodeficiency occurred in the 1950s. After a large number of studies, it was developed into an efficient non-infectious polio vaccine in 1977. This article describes the relationship between circulating antibodies produced after the vaccine immunization and immunological memory and long-term immunity to paralytic poliomyelitis.