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[目的]探讨介入治疗在肺癌治疗中的特点和局限性,为晚期肺癌的综合治疗提供理论依据。〔方法〕总结了近一年来接受支气管动脉灌注化疗的有纵隔淋巴结转移的晚期肺癌34例,并对原发灶与纵隔转移病灶各自对介入治疗的敏感性进行探讨。[结果]支气管动脉灌注化疗对肺癌原发灶的有效率为61.76%;对纵隔转移灶有效率为11.76%,两者比较有显著性差异(P<0.01)。〔结论〕支气管动脉灌注化疗对纵隔转移病灶的疗效远较原发灶疗效差,对此组患者应探索一种综合治疗手段,以期最大程度地提高治疗效果。
[Objective] To investigate the characteristics and limitations of interventional therapy in the treatment of lung cancer, and provide theoretical basis for the comprehensive treatment of advanced lung cancer. [Methods] Thirty-four patients with advanced lung cancer with mediastinal lymph node metastasis who underwent bronchial arterial infusion chemotherapy in the past year were reviewed. The sensitivity of interventional therapy for primary and mediastinal metastatic lesions was also investigated. [Results] The effective rate of bronchial artery infusion chemotherapy was 61.76% for primary lung cancer and 11.76% for mediastinal metastases. There was significant difference between the two (P<0.01). [Conclusion] Bronchial arterial infusion chemotherapy is less effective than primary tumor in the treatment of mediastinal metastases. This group of patients should explore a comprehensive treatment to maximize the treatment effect.