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目的:探讨甲氨蝶呤治疗类风湿关节炎的疗效。方法:选取2014/1-2015/1期间收治的60例类风湿关节炎患者作为研究对象,按照住院时间先后将全部患者分成观察组和对照组。对照组患者接受美洛昔康治疗,观察组患者在此基础之上接受甲氨蝶呤治疗,观察并对照两组疗效差异。结果:观察组患者的治疗总有效率明显高于对照组,两组差异具备统计学意义(P<0.05)。结论:甲氨蝶呤在类风湿关节炎患者的治疗当中效果显著,通过甲氨蝶呤联合美洛昔康可以显著提高治疗效果,降低不良反应发生率,值得临床应用与推广。
Objective: To investigate the efficacy of methotrexate in the treatment of rheumatoid arthritis. Methods: Sixty patients with rheumatoid arthritis who were treated during 2014 / 1-2015 / 1 were selected as the research objects. All patients were divided into observation group and control group according to the length of hospital stay. Patients in the control group were treated with meloxicam. Patients in the observation group received methotrexate on the basis of this observation, and the differences between the two groups were observed and compared. Results: The total effective rate of observation group was significantly higher than that of control group, the difference was statistically significant (P <0.05). Conclusion: Methotrexate is effective in the treatment of patients with rheumatoid arthritis. Methotrexate combined with meloxicam can significantly improve the therapeutic effect and reduce the incidence of adverse reactions, which deserves clinical application and promotion.