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目的:分析枣庄市2005年-2010年麻疹流行病学特点及血清学监测状况,为制定消除麻疹策略和措施提供依据。方法:采用酶联免疫吸附实验对枣庄市2005年-2010年采集的疑似麻疹病例血清进行IgM抗体检测。结果:检测疑似麻疹病例血清1 570份I,gM抗体阳性1 017份,阳性率64.78%。病例主要集中在1～6月份,占总病例数的85.94%(874/1017);年龄以<8月龄和8月龄～2岁儿童最高,占54.40%;20岁～组次之,占20.86%;以无免疫史者为主,有免疫史者占11.76%;城区与农村不同免疫史确诊病例所占比重有明显差异(χ2=8.56,P<0.05)。抗体阳转在出疹后3 d～14 d最高为68.59%(810/1181)。结论:加强常规免疫工作,提高适龄儿童的接种率和及时接种率;开展小月龄和成人麻疹病例的研究;以适应消除麻疹的需要。
OBJECTIVE: To analyze the epidemiological characteristics and serological surveillance of measles from 2005 to 2010 in Zaozhuang City, and to provide evidence for the development of measles elimination measures and measures. Methods: Enzyme linked immunosorbent assay was used to detect IgM antibody in the serum of suspected measles cases collected from 2005 to 2010 in Zaozhuang City. Results: A total of 1 017 serum samples of measles cases were detected, and 1017 were positive for gM antibody. The positive rate was 64.78%. The cases mainly concentrated in 1 ~ June, accounting for 85.94% (874/1017) of the total number of cases; the highest was in children <8 months old and 8 months old ~ 2 years old, accounting for 54.40%; the latter 20 years ~ 20.86%; those with no history of immunization and 11.66% of those with immunization history; the proportions of diagnosed cases of different immunization history in urban area and rural areas were significantly different (χ2 = 8.56, P <0.05). The positive rate of antibody positive was 68.59% (810/1181) at 3 d to 14 d after rash onset. CONCLUSIONS: Strengthening routine immunization work, raising the vaccination rate and timely vaccination rate of school-age children, conducting research on cases of small month-old and adult measles, and meeting the need of eliminating measles.