Design,synthesis and biological activity of novel herbicides targeted ALS(Ⅻ)--Quantitative structure

• 作 者: 杨光富 刘华银 杨秀凤 杨华铮
• 机 构: Institute of Organic Synthesis,Central China Normal University,Wuhan,Hubei 430079,China ,State Key L
• 出 处: Chinese Journal of Chemistry
• 发表日期: 1998年06期
• 关键词: pyrimidine quantitatively targeted hydrophobic benzene substituent preparing ani

The herbicidal activities of a series of 1,2,4-triazolo[1,5-a]pyrimidine-2-sulfonanilides containing various substituents on the benzene ring were quantitatively analyzed with physicochemi-cal parameters by using Hansch-Fujita method.Variations in the activity were parabolically related to electronic parameters with the optimum pKavalue being about 6.93.The hydrophobic factor in addition to the electronic property seemed to have important effect on the activity.

The herbicidal activities of a series of 1,2,4-triazolo [1,5-a] pyrimidine-2-sulfonanilides containing various substituents on the benzene ring were quantitatively analyzed with physicochemi-cal parameters by using Hansch-Fujita method. Variations in the activity were parabolically related to electronic parameters with the optimum pKavalue being about 6.93.The hydrophobic factor in addition to the electronic property seemed to have important effect on the activity.