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目的了解宁波市江东区男男性行为(MSM)人群HIV/AIDS抗病毒治疗效果。方法收集宁波市江东区2006—2013年抗病毒治疗管理的MSM人群HIV/AIDS资料,分析其服药依从性、治疗前后病毒载量和CD4+T淋巴细胞计数变化。结果 64例HIV/AIDS抗病毒治疗依从性为100.00%,不良反应发生率为26.56%,以骨髓抑制为主。CD4+T淋巴细胞计数在治疗后3个月内增长速度最快(环比=1.48)。患者在治疗后0、3、6、9和12个月时CD4+T淋巴细胞计数差异有统计学意义(P<0.05)。治疗满12个月后患者病毒载量均<50拷贝/m L。结论 MSM人群HIV/AIDS抗病毒治疗效果明显,特别是治疗后3个月。
Objective To understand the effect of anti-HIV treatment on HIV / AIDS among men who have sex with men (MSM) in Jiangdong District of Ningbo City. Methods HIV / AIDS data of MSM population collected from 2006 to 2013 in Jiangdong District of Ningbo City were collected and analyzed for drug adherence, viral load and CD4 + T lymphocyte count before and after treatment. Results 64 cases of HIV / AIDS anti-virus treatment compliance was 100.00%, the incidence of adverse reactions was 26.56%, mainly to bone marrow suppression. The CD4 + T lymphocyte count increased the fastest within 3 months after treatment (R = 1.48). The difference of CD4 + T lymphocyte count at 0, 3, 6, 9 and 12 months after treatment was statistically significant (P <0.05). The patient’s viral load was <50 copies / mL after 12 months of treatment. Conclusion The effect of HIV / AIDS antiviral treatment is obvious in MSM population, especially 3 months after treatment.