论文部分内容阅读
目的评价经导管肝动脉化疗栓塞术(TACE)联合门静脉化疗栓塞术(PVCE)治疗中晚期肝癌的疗效。方法中晚期肝癌患者43例,随机分为治疗组21例和对照组22例。分别采用TACE联合PVCE以及常规TACE的方法治疗。结果分别于术后1周和1月复查血清甲胎球蛋白(AFP)和肝脏CT。治疗组有效率较对照组高,2组差异有显著性(Ρ<0.05)。2组病例在手术前及术后1周肝功能指标均有变化,但2组之间指标的变化无显著性差异,4周后均恢复正常。结论TACE和PVCE联合治疗中晚期肝癌安全且疗效优于单独TACE技术。
Objective To evaluate the efficacy of transcatheter hepatic arterial chemoembolization (TACE) combined with portal vein chemoembolization (PVCE) in the treatment of advanced liver cancer. Methods 43 patients with advanced hepatocellular carcinoma were randomly divided into treatment group (n = 21) and control group (n = 22). TACE combined with PVCE and conventional TACE treatment. Results Serum AFP and CT were observed at 1 week and 1 month after operation respectively. The effective rate of the treatment group was higher than that of the control group, with significant difference between the two groups (P <0.05). There were changes of liver function indexes in the two groups before and 1 week after operation, but there was no significant difference in index between the two groups, and returned to normal after 4 weeks. Conclusion The combination of TACE and PVCE in the treatment of advanced hepatocellular carcinoma is safe and effective than TACE alone.