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作者对20名深部白念珠菌感染病人(活动期或好转期)以及16名其他病种患者。25名健康人和20份脐血进行了特异性白细胞移动抑制试验(LMIT),除白念珠菌感染活动期及脐血的移动指数(MI)小于0.8外,其余的MI均大于0.8。作者同时又对白念珠菌感染者中的15例测定了非特异抗原PHA的MI,结果无论活动期或好转期均小于0.8。作者认为特异性LMIT比较敏感,特异性高,重复性好,可作为深部念珠菌病诊断、观察疗效和判断预后的指标。
The authors of 20 patients with deep Candida infection (active or remission) and 16 other patients with disease. Twenty-five healthy individuals and 20 cord blood samples were tested for leukocyte migration inhibition (LMIT). Except for Candida albicans infection and cord blood migration index (MI) less than 0.8, the remaining MIs were all greater than 0.8. At the same time, the authors also measured the MI of non-specific antigen PHA in 15 of the Candida albicans infected patients, with the result that both the activity and the turn-around were less than 0.8. The authors believe that specific LMIT is more sensitive, specific and reproducible, which can be used as an indicator of deep candidiasis diagnosis, observation of curative effect and judgment of prognosis.