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目的了解广州地区无偿献血人群HBsAg阳性的流行状况,为制定及招募安全血源提供科学依据。方法回顾性调查分析广州地区2000年1月至2010年12月无偿献血人群2 520 179例,对HBsAg检测结果进行统计分析。结果2000-2010年广州地区无偿献血者HBsAg阳性率为0.93%,其中2007-2010年间HBsAg阳性率有升高趋势(χ2=61.024,P<0.001)。HBsAg阳性率在不同性别、年龄、职业、学历间差异均有统计学意义(χ2=3596,P<0.001;χ2=442.6,P<0.001;χ2=216.4,P<0.001;χ2=2013.0,P<0.001)。男性HBsAg阳性率高于女性;18～岁组HBsAg阳性率低于其他年龄组;工人、农民及学历较低者有较高的HBsAg阳性率。结论广州地区无偿献血人群HBsAg保持较平稳流行率,2007-2010年有升高趋势,应进一步加强乙肝防控工作。鼓励年青人献血更有利于保障临床输血安全。
Objective To understand the prevalence of HBsAg positive in unpaid blood donors in Guangzhou and provide a scientific basis for the establishment and recruitment of safe blood. Methods A retrospective survey was conducted to analyze 2 520 179 cases of unpaid blood donation from January 2000 to December 2010 in Guangzhou. The results of HBsAg test were statistically analyzed. Results The positive rate of HBsAg in unpaid blood donors in Guangzhou from 2000 to 2010 was 0.93%, and the positive rate of HBsAg in 2007-2010 increased (χ2 = 61.024, P <0.001). The positive rate of HBsAg in different gender, age, occupation and education were statistically significant (χ2 = 3596, P <0.001; χ2 = 442.6, P <0.001; χ2 = 216.4, P <0.001; χ2 = 2013.0, P < 0.001). The positive rate of HBsAg in males was higher than that in females. The positive rate of HBsAg in 18 ~ year group was lower than that in other age groups. Workers, peasants and people with lower education level had higher HBsAg positive rate. Conclusion HBsAg in unpaid blood donors in Guangzhou maintained a relatively steady prevalence rate, with an increasing trend from 2007 to 2010, and prevention and control of hepatitis B should be further strengthened. Encouraging young people to donate blood is more conducive to the protection of clinical blood transfusion safety.