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目的 观察急性心梗患者入院后血清心肌肌钙蛋白 I(c Tn I)的变化 ,探讨其与心梗预后的关系。方法 6 2例 AMI患者 2 4小时内、第 2天、第 5天各采血一次。用免疫吸附分析法定量测定血浆 c Tn I水平 ,分析其与预后的关系。结果 AMI患者第 2天测定的 c Tn I值最高 ,在并发有严重急性左心衰、休克及死亡的 AMI病例中 c Tn I水平显著高于无这些并发症的患者 (P<0 .0 5 )。而单纯并发有重度房室传导阻滞和 (或 )严重室性心律失常的 AMI患者与无此并发症的患者比较 c Tn I水平无显著差异 ;而不同部位心梗其 c Tn I水平比较无显著差异。结论 定量测定血清 c Tn I水平对心梗预后有一定指导意义。
Objective To observe the changes of serum cardiac troponin I (cTn I) after admission in acute myocardial infarction (AMI) patients and explore its relationship with the prognosis of myocardial infarction. Methods Sixty-two AMI patients within 24 hours, the first two days, five days of blood sampling. The level of plasma cTn I was measured by immunoadsorption assay and its relationship with prognosis was analyzed. Results The AMI patients had the highest cTnI value measured on the second day. The level of cTnI was significantly higher in AMI patients with severe acute left heart failure, shock and death than those without these complications (P <0.05 ). However, there was no significant difference in cTnI levels between AMI patients with simple AV block and / or severe ventricular arrhythmia and those with no such complications. The levels of cTnI in MI with different locations were no significant difference Significant differences. Conclusion The quantitative determination of serum cTn I level has a guiding significance for the prognosis of myocardial infarction.