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用全自动生化分析仪、气相色谱等方法测定了轻度、中度和重度妊娠高血压综合征患者、正常孕妇、正常已婚未孕妇女红细胞膜胆固醇、磷脂和脂肪酸的含量,其中轻度、中度、重度妊娠高血压综合征分别为15例、11例、10例,正常孕妇、已婚未孕妇女分别为24例、22例。结果:中度、重度妊娠高血压综合征组红细胞膜的胆固醇、胆固醇磷脂比值较正常妊娠组、正常已婚未孕组明显增高(P<001),轻度妊娠高血压综合征、正常妊娠组、正常已婚未孕组红细胞膜的胆固醇、胆固醇磷脂比值无显著性差异(P>005)。提示:红细胞膜的成分变化与妊娠高血压综合征的发病有一定关系
The levels of cholesterol, phospholipids and fatty acids in the erythrocyte membrane of mild, moderate and severe pregnancy induced hypertension patients, normal pregnant women and normal pregnant women were measured by automatic biochemical analyzer and gas chromatography. Moderate and severe pregnancy-induced hypertension syndrome were 15 cases, 11 cases, 10 cases, normal pregnant women, married and pregnant women were 24 cases, 22 cases. Results: The ratio of cholesterol and phospholipid cholesterol in erythrocyte membrane in moderate and severe pregnancy induced hypertension syndrome group was significantly higher than that in normal pregnancy group (P <001), mild pregnancy-induced hypertension syndrome In the pregnancy group, there was no significant difference in cholesterol and phospholipid cholesterol between normal married and non-pregnant groups (P> 005). Tip: changes in composition of erythrocyte membrane and the incidence of pregnancy-induced hypertension have a certain relationship