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巨噬细胞的活化是白间素-1释放的基础。一些微生物及其产物和其它试药能有效地激活巨噬细胞。最近指出药用植物松果菊属和野靛属也能激活巨噬细胞。本文研究了紫松果菊(Echinaceapurpurea)、狭叶松果菊(E.angustifolia)和野靛属植物Baptisia tinctoria中的多聚物对白间素-1的影响。将P388D_1细胞株培养0～72 h后的巨噬细胞培养液的上清液经渗析过滤后,用分裂繁殖试验测定白间素-1的浓度(先画出已知量0.5～0.05 u/ml的白间素标准曲线)。当加入抗小鼠白间素-1的血清时,白
The activation of macrophages is the basis for the release of interleukin-1. Some microorganisms and their products and other reagents can effectively activate macrophages. It has recently been pointed out that the medicinal plants Echinacea and Pheasant also activate macrophages. In this paper, the effects of polymers from Echinacea purpurea, E. angustifolia and Baptisia tinctoria on interleukin-1 were studied. After the P388D_1 cell strain was cultured for 0 to 72 hours, the supernatant of the macrophage culture medium was dialyzed and filtered, and the concentration of interleukin-1 was determined by a splitting propagation test (the known amount was 0.5 to 0.05 u/ml. Interleukin standard curve). When anti-mouse interleukin-1 serum is added, white