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β受体阻滞剂常用于治疗高血压等疾患,作者复习文献,就其在妊娠期的应用及安全性进行评价。基于肾上腺素能对母、胎生理影响的实验研究以及大量的临床经验,认为在妊娠头三月后至分娩前2～3天,应用具有β_1选择性、内源性交感活性或α阻滞活性的β阻滞剂,例如美多心安、氨酰心安、心得平、醋丁酰心安、心得静、柳胺苄心定,对胎儿儿无风险,对母亲能有益处。
Beta blockers commonly used in the treatment of hypertension and other diseases, the authors review the literature on its application and safety during pregnancy evaluation. Based on the adrenergic study of the effects of adolescents and fetuses on the physiology of the fetus and fetus, as well as a large amount of clinical experience, it is believed that the use of β1 -selective, endogenous sympathetic or α-blocker activity from the first trimester to the second to the third day before labor Beta blockers, such as metoprolol, atenolol, placenta, butacyl palmitate, calm, carbendazin, risk-free for the fetus, the mother can benefit.