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《本草纲目》记载狼毒主治“积聚”、“恶疮”、“胁下积癖”、“痰饮癥瘕”,有些病症可能属恶性肿瘤。我们曾报道瑞香狼毒对小鼠移植肿瘤S_(180)、U_(14)、肝癌的抑制作用[中药通报1986,11(1):58]。本文仅报道它对小鼠移植性Lewis 肺癌生长的抑制作用。材料药物狼毒采自内蒙,系瑞香科瑞香狼毒(Stellera chamaejasme L.)的干燥根。将饮片分别用水煮醇沉法和乙醇热提法得其水提物和酒提物。
The “Compendium of Materia Medica” records the wolf poison attendance “accumulation”, “evil sore”, “under threat accumulation of phlegm,” “drinking phlegm,” and some of the conditions may be malignant. We have reported the inhibitory effect of Stellera chamaejasme on mice transplanted with tumors S_(180), U_(14), and liver cancer [Chinese Traditional Medicine Bulletin 1986, 11(1):58]. This article only reports its inhibitory effect on the growth of transplanted Lewis lung cancer in mice. The material drug wolf poison was collected from Inner Mongolia and was the dry root of Stellera chamaejasme L.. The water extracts and wine extracts were obtained from the decoction pieces using the boiled alcohol precipitation method and the ethanol thermal extraction method, respectively.