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目的:探讨宫颈电环切除术(LEEP)术后至妊娠的时间间隔对妊娠结局的影响。方法:收集2000年~2010年LEEP术后准备生育的106例妇女为病例组,随机抽取同期门诊准备生育、无宫颈治疗史的106例健康妇女为对照组。比较两组的妊娠率及妊娠方式。按LEEP术后至受孕的时间间隔,将病例组中妊娠者分为3组:术后12月内、术后13~24月和25月后组,比较3组孕妇的妊娠结局。结果:病例组中1例失访。病例组与对照组的妊娠率分别为98.10%(103/105)和99.06%(105/106);自然妊娠率分别为99.03%(102/105)和99.05%(104/106);剖宫产率分别为37.14(39/105)和35.85%(38/106),两组比较均无显著差异(P>0.05)。两组的剖宫产原因不同,病例组中因高龄因素行剖宫产者显著高于对照组(P=0.001)。病例组中术后12个月内、13~24个月和25个月后妊娠者分别有27例、43例和32例,3组的流产、早产、胎膜早破和剖宫产率均无显著差异(P>0.05)。结论:LEEP术后至妊娠的时间间隔不影响患者的受孕及妊娠结局。
Objective: To investigate the effect of cervical electrocautery excision (LEEP) after operation to pregnancy on pregnancy outcome. Methods: A total of 106 women who underwent LEEP from 2000 to 2010 were enrolled as the case group, and 106 healthy women with the history of cervical pregnancy were selected randomly as the control group. The pregnancy rates and gestational patterns of the two groups were compared. According to the time interval after the operation of LEEP to conception, the pregnant women in the case group were divided into 3 groups: within 12 months after operation, after 13 to 24 months and after 25 months after operation, the pregnancy outcomes of 3 groups of pregnant women were compared. Results: One case was lost in case group. The pregnancy rates of cases and controls were 98.10% (103/105) and 99.06% (105/106) respectively. The rates of natural pregnancy were 99.03% (102/105) and 99.05% (104/106) respectively. Cesarean section Rates were 37.14 (39/105) and 35.85% (38/106), respectively, with no significant difference between the two groups (P> 0.05). Caesarean section in both groups was attributed to different causes. Caesarean section was significantly higher in the case group due to age-related factors than in the control group (P = 0.001). In the case group, there were 27 cases in the 12 months after operation, 13 cases in 24 months and 25 months after pregnancy, 43 cases and 32 cases in 3 groups. The rates of miscarriage, premature labor, premature rupture of membranes and cesarean section No significant difference (P> 0.05). CONCLUSION: The time between postoperative LEEP and pregnancy does not affect the pregnancy and pregnancy outcome of patients.