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从中国台湾省的药用植物 P.pleianthum 中曾分离得几个具有抗肿瘤活性的木脂体化合物。作者从该植物的根和根茎的苯提取液中分得一新的酮基木脂体。取苯提液经柱层析和制备性薄层层析分离,从甲醇得无色针状结晶,得率为0.013%。分子式 C_(22)H_O(20)O_8,熔点170～172°,[α]_D-273°(氯仿)。经 UV、IR、NMR、MS 等分析及与已知合成化合物对照,确定为异鬼柏苦酮(I,Isopicropodo-phyllone)。
Several antitumor lignan compounds have been isolated from P.pleianthum, a medicinal plant in Taiwan Province of China. The authors obtained a new ketone-based lignan from the plant’s root and rhizome benzene extracts. The benzene extracts were separated by column chromatography and preparative thin layer chromatography, colorless needles crystallized from methanol, yield 0.013%. Molecular formula C_ (22) H_O (20) O_8, melting point 170 ~ 172 °, [α] -D-273 ° (chloroform). It was identified as Isopicropodo-phyllone by UV, IR, NMR, MS and other known synthetic compounds.