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WHO 推测全世界乙肝病毒(HBV)携带者约2亿人,80%在亚洲。我国是HBV 携带者高发地区之一,平均携带率约8.83%,孕妇携带率2.6～12.5%。HBsAg 携带妇女尤其合并e 抗原阳性者可在产前、产时或产后传播给婴儿,感染率92～97%,其中80～90%的婴儿变成慢性携带者。估计我国的携带者40%由于母婴传播造成,形成大量传染源。少数出生的婴儿表现急性或重症肝炎,有报道病例仅HBsAg携带母亲出生婴儿暴发性肝炎死亡。在围产期或婴儿
WHO estimates about 200 million people with hepatitis B virus (HBV) carriers worldwide, 80% in Asia. China is one of the high incidence areas of HBV carriers with an average carrying rate of about 8.83% and a carrying rate of 2.6 to 12.5% of pregnant women. HBsAg-carrying women, especially those with positive e-antigen, can be transmitted to infants during prenatal, during or after delivery with an infection rate of 92-97%, of whom 80-90% of infants become chronic carriers. It is estimated that 40% of the carriers of our country are caused by mother-to-child transmission, resulting in a large number of sources of infection. A small number of infants showed acute or severe hepatitis, and only HBsAg-borne hepatitis was reported in mothers. During perinatal or infant