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观察肾嫌色细胞癌的病理特点并与其它肾上皮性肿瘤鉴别。方法在光镜观察基础上，运用免疫组织化学检测ＣＫ８及Ｖｉｍｅｎｔｉｎ，并行Ｈａｌｅ胶体铁染色及电镜检查来观察７例肾嫌色细胞癌。并对７例病人进了随访。结果嫌色细胞癌由两种细胞类型组成，即典型型及嗜酸型。这些细胞的特点是ＣＫ８阳性，Ｖｉｍｅｎｔｉｎ阴性，Ｈａｌｅ胶体铁阳性，电镜下见大量胞浆内的单层膜构成的小空泡。随访３～１２６个月（平均７０个月），７例病人均无肿瘤复发及转移并存活至今。结论嫌色细胞癌是具有独特的形态特点及较好预后的肿瘤。根据组织学改变及辅助检测方法，可与其它肾上皮性肿瘤鉴别，具有临床意义。
To observe the pathological features of chromophobe renal cell carcinoma and identify with other renal epithelial tumors. Methods On the basis of light microscopy, CK8 and Vimentin were detected by immunohistochemical staining and Hale colloid iron staining and electron microscopy were used to observe 7 cases of chromophobe renal cell carcinoma. Seven patients were followed up. The results of chromophobe carcinoma by the two cell types, namely, typical and eosinophilic. These cells are characterized by positive CK8, Vimentin negative, Hale colloidal iron positive, electron microscopy see a large number of cytoplasmic monolayers of small vacuoles. All cases were followed up for 3 ~ 126 months (average 70 months). None of the 7 patients had tumor recurrence and metastasis and survived so far. Conclusion Chromophoblastic carcinoma is a tumor with unique morphological characteristics and good prognosis. According to histological changes and auxiliary detection methods, with the identification of other renal epithelial tumors, with clinical significance.