硫酸锌治疗声带肉芽肿

• 作 者: 萧新民
• 出 处: 国外医学参考资料.耳鼻咽喉科学分册
• 发表日期: 1977年03期
• 关键词: 肉芽肿 接触性溃疡 声带 接触性肉芽肿 声门下狭窄 气管插管麻醉 人工呼吸器 剂量 声带突 声门

气管插管麻醉后常引起声带肉芽肿(女性多见);其次为接触性溃疡或接触性肉芽肿(常发生于男性)。以上合并症之发生率约占1/1000;插管后如伴用人工呼吸器,其合并症之发生率更高,约4％。 Pullen(1970)首次提出口服硫酸锌治疗气管插管后肉芽肿、声门及声门下狭窄,取得良好效果,本文报告6例。4例插管后肉芽肿(成人3、小儿1);2例接触性溃疡肉芽肿(成人2)。用药剂量:成人220毫克一日三次;小儿50毫克一日三次。服药2—3周后症状减轻;3个月后肉芽肿消退。全部病例未见复发。

Tracheal intubation often lead to vocal cord granuloma after anesthesia (more common in women); followed by contact ulcers or contact granulomas (often occurs in men). The incidence of these complications is about 1/1000; after intubation if accompanied by respirators, the incidence of complications is higher, about 4%. Pullen (1970) first proposed oral zinc sulfate for the treatment of post-tracheal intubation granuloma, glottis and subglottic stenosis, and achieved good results, the paper reported six cases. 4 cases of granuloma after intubation (adult 3, children 1); 2 cases of contact ulcer granuloma (adult 2). Dosage: Adult 220 mg three times a day; children 50 mg three times a day. Symptoms were relieved after 2-3 weeks of treatment; granulomas subsided after 3 months. No recurrence in all cases.