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本文应用免疫放射分析法(IRMA)测定52名正常人和44例地甲肿流行区健康人血清TSH、FT_4和FT_3。并对28例甲亢患者、11例甲低患者、13例甲亢治疗后患者及51例地方性克汀病患者和96例地方性甲状腺肿大病人的血清TSH,FT_4和FT_3结果进行分析。甲亢患者血清TSH水平显著低于正常组(P<0.001);甲低患者显著高于正常组(P<0.001)。血清甲状腺激素及TSH实验室测定值能较好地符合上述各试验组的临床诊断,表明本法是一种较灵敏、准确的血清TSH分析方法。
In this paper, the serum TSH, FT_4 and FT_3 of 52 healthy people and 44 healthy people with dendritic edema were detected by immuno-radiometric assay (IRMA). The serum levels of TSH, FT_4 and FT_3 in 28 cases of hyperthyroidism, 11 cases of hypothyroidism, 13 cases of hyperthyroidism and 51 cases of endemic cretinism and 96 cases of endemic goiter were analyzed. Serum TSH levels in patients with hyperthyroidism were significantly lower than those in normal controls (P <0.001); patients with hypothyroidism were significantly higher than those in controls (P <0.001). Serum thyroid hormone and TSH laboratory measured values can better meet the clinical diagnosis of the above test groups, indicating that this method is a more sensitive and accurate serum TSH analysis.