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目的:观察玉女煎联合复合维生素B治疗反复发作性口腔溃疡的临床疗效。方法:将146例复发作口腔溃疡患者随机分为对照组和治疗组。对照组70例予复合维生素B治疗,治疗组70例在对照组治疗基础上加服玉女煎治疗。观察两组患者治疗前后血清中C-反应蛋白量的变化及在1年时间中溃疡发作的次数和临床疗效。结果:治疗后,治疗组患者血清中C-反应蛋白含量明显低于对照组,差异有统计学意义(P<0.05)。治疗后,治疗组和对照组1年内发作次数分别为(0.8±0.2)次、(3.2±0.9)次,两组比较,差异有统计学意义(P<0.05)。对照组总有效率为74.3%,治疗组总有效率为88.6%,两组比较,差异有统计学意义(P<0.05)。结论:玉女煎联合复合维生素B治疗反复发作性口腔溃疡的临床疗效显著,能有效降低患者复发的次数。
Objective: To observe the clinical efficacy of jade female decoction combined with vitamin B in the treatment of recurrent oral ulcer. Methods: 146 patients with recurrent oral ulcer were randomly divided into control group and treatment group. The control group of 70 patients treated with vitamin B, the treatment group of 70 patients in the control group based on the treatment plus jade female fry treatment. The change of serum C-reactive protein in two groups before and after treatment and the number of ulcer attack and clinical efficacy in one year were observed. Results: After treatment, the content of serum C-reactive protein in the treatment group was significantly lower than that in the control group, the difference was statistically significant (P <0.05). After treatment, the number of attacks in the treatment group and the control group within one year were (0.8 ± 0.2) times and (3.2 ± 0.9) times, respectively. There was significant difference between the two groups (P <0.05). The total effective rate of the control group was 74.3%, the total effective rate of the treatment group was 88.6%, the difference between the two groups was statistically significant (P <0.05). Conclusion: Jade female decoction combined with vitamin B treatment of recurrent oral ulcer clinical significant effect, can effectively reduce the number of patients relapse.