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调查104例胃癌患者及其一级亲属的发病情况.引用Falconer的会计阀值性状遗传度公式,得到石河子地区胃癌遗传度为44.2%±6.6%。进一步分析发现,弥漫浸润型胃癌具有更高的遗传度(58.8%±11.7%),为该类型胃癌发生多有遗传因素参与的假说提供了佐证。
The incidence of 104 patients with gastric cancer and their first-degree relatives was investigated. According to Falconer’s accounting threshold trait heritability formula, the heritability of gastric cancer in Shihezi area was 44.2%±6.6%. Further analysis found that diffuse infiltrative gastric cancer has a higher heritability (58.8% ± 11.7%), providing evidence for the hypothesis that this type of gastric cancer has multiple genetic factors involved.