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[目的]掌握住院严重急性呼吸道感染(SARI)病例甲型H1N1流感病毒感染情况,为流感防治工作提供依据。[方法]2009年第48周至2010年第12周,对济宁市县级及以上医疗机构报告的208例住院SARI病例进行调查与流感病原检测。[结果]208例SARI病例中,70.19%有慢性病或为孕产妇,20～49岁占62.12%;流感病毒核酸阳性率为32.69%,其中甲型H1N1流感病毒核酸阳性率为18.27%,季节性H1N1型流感病毒核酸阳性率为0.48%,H3N2型流感病毒核酸阳性率为8.65%,B型流感病毒核酸阳性率为5.29%。208例住院SARI病例病死率为2.88%,其中甲型H1N1流感危重症病例2例死亡。[结论]住院SARI病例甲型H1N1流感病毒感染率较高。
[Objective] To understand the infection of influenza A (H1N1) virus in hospitalized patients with severe acute respiratory infection (SARI) and provide basis for prevention and treatment of influenza. [Methods] From the 48th week of 2009 to the 12th week of 2010, 208 cases of in-hospital SARI reported by medical institutions at county level and above in Jining City were investigated and the pathogen of influenza was detected. [Results] Among the 208 SARI cases, 70.19% had chronic diseases or were pregnant women, accounting for 62.12% of those aged 20-49 years; the positive rate of influenza virus nucleic acid was 32.69%, and the positive rate of influenza A (H1N1) virus was 18.27% H1N1 influenza virus nucleic acid positive rate was 0.48%, H3N2 influenza virus nucleic acid positive rate was 8.65%, influenza B virus nucleic acid positive rate was 5.29%. 208 cases of hospitalized SARI case fatality rate was 2.88%, of which 2 cases of critical illness of influenza A (H1N1) died. [Conclusion] The infection rate of influenza A (H1N1) virus in hospitalized SARI cases is high.