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目的：用电子自旋共振（ Ｅ Ｓ Ｒ）法测定牙釉质自由基来估算广岛原爆幸存者的 γ射线吸收剂量，并与细胞遗传学研究结果相比较。方法：对 ６９ 位原爆幸存者提供的１００ 只牙的牙釉质进行了 Ｅ Ｓ Ｒ 测定，并对其中的 ６１ 位供牙者进行了常规的细胞遗传学检查。牙的 Ｘ 射线照射主要影响牙颊面，为了评估γ射线可能造成的污染，每只牙分成颊面和舌面两部分，然后分别进行釉质分离及 Ｅ Ｓ Ｒ 测定。结果：有将近 ２０ 只牙的颊面剂量高于舌面，这些牙大多为切牙和犬牙，此结果可能由于阳光的照射。与切牙和犬牙不同，磨牙颊面和舌面的剂量则是相近似。４０ 位原爆幸存者磨牙的 Ｅ Ｓ Ｒ 测得的剂量与常规细胞遗传学（淋巴细胞染色体易位）分析得到的剂量效应曲线、与离体 γ射线照射实验的预期结果几乎相同。结论：即使在事故后半个世纪，牙釉质的 Ｅ Ｓ Ｒ测定和淋巴细胞遗传学分析对于急性照射事故的个人剂量估算仍然是很有价值的。
OBJECTIVE: To estimate γ-ray absorbed dose of enamel free radical in ESR patients by electron spin resonance (E S R) method and to compare with the results of cytogenetics. METHODS: The ESR of 100 enamel provided by 69 primary blast survivors was measured and 61 of them were routinely examined by cytogenetics. Tooth X-ray irradiation mainly affects the buccal surface. In order to evaluate the possible contamination caused by gamma rays, each tooth is divided into two parts: the buccal surface and the lingual surface. Enamel separation and E S R measurement are performed separately. RESULTS: There were nearly 20 buccal buccal surfaces above the tongue. Most of these teeth were incisors and canines, which may be due to exposure to sunlight. Unlike incisors and canines, the buccal and lingual doses are similar. The dose-response curves obtained from the E S R measurements of 40 primary blast survivors with conventional cytogenetics (lymphocyte chromosomal translocations) were approximately the same as expected from in vitro γ-ray irradiation experiments. Conclusions: Even after half an century after the accident, E-R enamel measurement and lymphocytic genetic analysis are still valuable for personal dose estimation of acute exposure events.