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作者报告1947年～1970年间所收集的细支气管—肺泡癌共29例。其中24例曾作肺切除术,1例作剖胸活检,3例作肺穿刺活检,另1例系痰脱落细胞检查证实。所有病例的临床和组织病理学检查均符合原发性细支气管—肺泡癌的诊断。作者根据病理解剖检查资料,将本组病例分成三大组。第一组:肿瘤呈2～8厘米直径的单个病灶或单个结节形,局限于一个肺叶内,共11例。其中8例病灶边缘清晰,3例则境界较模糊,对邻近肺组织有轻度浸润。本组中有10例未见淋巴结或胸膜转移。第二组:共10例。3例为多发性肺实质性病灶或肺内多个结节性病灶,5例为多个结节融合的表现,均局限于一个肺叶内。另2例为灰色肺炎性实变,局限于一个肺叶内。与第一组不同,肿瘤侵犯胸膜或淋巴结的病例占50％。除1例仅作单纯剖胸探查术外,其余病例均作了切除手术。第三组:共8例。单个肿瘤超过一个肺叶以上。局限于一侧者3例,肿瘤为双侧性者1例,均作了外科切除术。本组还包括4例病变广泛未能作手术切除者(3例肺穿刺活检,1例痰脱落细胞检查)。患者的年龄自22岁～75岁,平均50岁,60岁～59
The authors report a total of 29 cases of bronchiolar-alveolar carcinoma collected between 1947 and 1970. Twenty-four patients had pneumonectomy, one had a thoracotomy biopsy, three had a lung biopsy, and the other had a sputum exfoliated cell test. Clinical and histopathological examinations of all cases were in line with the diagnosis of primary bronchiole-alveolar carcinoma. According to the pathological anatomical examination data, the author divided the group into three groups. The first group consisted of a single lesion with a diameter of 2-8 cm or a single nodular shape confined to one lobe with a total of 11 cases. Among them, 8 cases had clear edges, 3 cases had a more ambiguous border and mild infiltration of adjacent lung tissue. Ten patients in this group had no lymph node or pleural metastasis. The second group: a total of 10 cases. Three patients had multiple primary pulmonary lesions or multiple nodular lesions in the lung. Five patients had multiple nodular fusions and were confined to one lobe. The other two cases were gray pneumonia constrictions confined within one lobe. Unlike the first group, 50% of the cases were tumor invading the pleura or lymph nodes. Except for one case of simple thoracotomy exploration, all other cases were resectioned. The third group: a total of 8 cases. A single tumor has more than one lobe above. Three patients were confined to one side and one patient had bilateral tumors. All patients underwent surgical resection. This group also included 4 patients with extensive lesions that were not able to undergo surgical resection (3 lung biopsies and 1 sputum cytology). The patient’s age ranged from 22 to 75 years old, with an average of 50 years old and 60 to 59 years old.