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弥漫性血管内凝血(简称DIC),是一种由多种因素引起的病理生理过程,是凝血机能异常的综合征。由于具有促凝特性的物质进入血管内,使血液处于高凝状态,以致发生微循环内广泛的血管内凝血,微血栓形成。随着血栓形成的发展,凝血因子及血小板大量消耗,终至凝血因子缺乏,使血液处于低凝状态,导致出血倾向,发生凝血障碍,有人称为消耗性凝血障碍(Consumption Coagulopatby)。在凝血过程中,纤维蛋白元不断转变成纤维蛋白,若纤维蛋白元的产生不能补偿耗损,则血浆浓度不断减低,故又称去纤维蛋白元综合征(Defibrination Syndrome),目前大多数人还是称为弥漫性血管内凝血。
Diffuse intravascular coagulation (DIC), is a pathophysiological process caused by a variety of factors, is a syndrome of coagulation dysfunction. Due to procoagulant substances into the blood vessels, the blood in a hypercoagulable state, resulting in a wide range of microvascular coagulation, micro-thrombosis. With the development of thrombosis, clotting factors and platelets are consumed in large quantities, and finally the lack of coagulation factors causes the blood to be in a low coagulation state, leading to bleeding tendency and coagulation disorder, which is called consumptive coagulation disorder. In the process of coagulation, fibrin yuan continuously transformed into fibrin, fibrin yuan if the production can not compensate for wear and tear, the plasma concentration continues to decrease, it is also known as defibrotide (Defibrination Syndrome), most people still said Diffuse intravascular coagulation.