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采用双抗体夹心ＥＬＩＳＡ法测定３６ 例正常妊娠妇女及８５ 例胎膜早破患者脐血白细胞介素６（ＩＬ６） 和白细胞介素８（ＩＬ８） 水平。结果发现：胎膜早破合并临床绒毛膜羊膜炎者、病理诊断绒毛膜羊膜炎者及新生儿感染者，其脐血ＩＬ６ 和ＩＬ８ 水平明显高于正常妊娠妇女，胎膜早破未合并感染者及未感染新生儿，差异有显著性意义（Ｐ＜ ０－０１） 。提示：脐血ＩＬ６ 和ＩＬ８ 水平升高可作为胎膜早破合并宫内感染及新生儿感染的指标，用于指导新生儿抗感染治疗。
The levels of interleukin-6 (IL6) and interleukin-8 (IL8) in umbilical cord blood of 36 normal pregnant women and 85 premature ruptured membranes were measured by double antibody sandwich ELISA. The results showed that: premature rupture of membranes combined with clinical chorioamnionitis, pathological diagnosis of chorioamnionitis and neonatal infections, umbilical cord blood IL6 and IL8 levels were significantly higher than normal pregnant women, premature rupture of membranes did not merge Infected and non-infected newborns, the difference was significant (P <0-01). Tip: Umbilical cord blood IL 6 and IL 8 levels can be used as premature rupture of membranes with intrauterine infection and neonatal infection indicators, used to guide the neonatal anti-infective treatment.