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对35例卵巢颗粒细胞瘤患者的临床病理资料进行回顾性分析。全部患者均接受过至少一次手术治疗,采取单纯手术6例,术后辅助放疗7例,术后辅助化疗13例,辅以放疗+化疗9例。结果:按寿命表法统计,3年、5年生存率分别为87.3%、75.8%,伴有子宫内膜增生者占34.3%。认为卵巢颗粒细胞瘤的治疗应采用以手术为主的综合疗法,除Ia期外,单纯手术治疗复发率高。术后辅以联合化疗是减少肿瘤复发、提高生存率的有效措施。
The clinical and pathological data of 35 patients with ovarian granulosa cell carcinoma were retrospectively analyzed. All patients underwent at least one surgical treatment. Six cases were treated by simple operation, 7 cases were postoperative adjuvant radiotherapy, 13 cases were postoperative adjuvant chemotherapy and 9 cases were treated with radiotherapy and chemotherapy. Results: According to the statistic of life table, the 3-year and 5-year survival rates were 87.3% and 75.8% respectively, while the patients with endometrial hyperplasia accounted for 34.3%. That the treatment of ovarian granulosa cell tumor should be based on the use of a comprehensive treatment, in addition to Ia, simple surgical treatment of recurrence rate. Postoperative adjuvant chemotherapy is to reduce tumor recurrence and improve the survival rate of effective measures.