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用病毒—红细胞—糖悬液经口感染埃及伊蚊13个地理株以比较它对登革热病毒的敏感性。观察到不同地理株对四种登革热血清型的敏感性有显著差异,蚊株对某一种血清型较敏感,同样地对另一些血清型也较敏感,从而提示控制敏感性因素对所有四型是相同的,地理株的敏感性与经口感染蚊需要的病毒数目是相反的关系,对登革热的1～4型的感染阈是不同的,新近分离的登革热1型和3型株与原型株之间在敏感性上没有什么不同,用4个地理株进行杂交试验结果,杂种子一代具有象杂交复壮的相同敏感性,观察到蚊株的敏感性和抗性之间在比率、用肠胃外途径感染后病毒复制的数目或用经口途径感染后传播登革热2型病毒的能力上是不同的。
Thirteen geographic strains of Aedes aegypti were orally infected with a virus-erythrocyte-sugar suspension to compare their susceptibility to dengue virus. It was observed that the sensitivity of different geographical strains to the four dengue serogroups was significantly different. The mosquito was more sensitive to one serotype and similarly sensitive to other serotypes, suggesting that controlling the susceptibility to all four types Is the same, the sensitivity of the geographic strain is inversely related to the number of viruses required to orally infect mosquitoes and is different for the infection thresholds of type 1 to 4 of dengue fever. The newly isolated dengue type 1 and type 3 strains and the prototype strain There was no difference in sensitivity between the two strains. The results of the hybridization test with four geographic strains showed that the hybrids had the same sensitivity as hybrid vigor, the ratio between susceptibility and resistance of mosquitoes was observed with parenteral Pathway The number of viral replication after infection or the ability to transmit dengue 2 virus after infection by the oral route is different.