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目的:探讨硝酸甘油介入心肌断层显像在心肌存活评价的临床应用价值,方法:应用静息、硝酸甘油介入99mTC-MIBI心肌血流灌注断层显像,对20例不稳定型心绞痛患者(其中8例有陈旧性心梗病史)PTCA术前术后进行自身对比分析。结果:20例患者160个心肌节段中、静息显像异常积分为196(1分33个节段、2分20个节段、3分41个节段):硝酸甘油介入显像及PTCA术后静息显像异常积分均较术前静息显像明显减少且两者积分接近,分别为104和97分。而核素分布正常节段分别增加46和53个心肌节段增加67.7%,77.9%,两者相似(P>0.05),两者和术前静息显像相比有显著差异(P<0.01)。术前患者射血分数为44.5±12.6%,术后为56.4±16.3%,增加26.8%。结论:揭示核素心肌硝酸甘油介入心肌断层显像对存活心肌评价简便无创,客观准确,为心绞痛患者PTCA术前选择适应症及术后评价疗效提供了有力手段
Objective: To investigate the clinical value of nitroglycerin interventional myocardial imaging in the evaluation of myocardial viability. Methods: Resting and nitroglycerin interventional 99mTC-MIBI myocardial perfusion tomography were used to evaluate the clinical value of 20 patients with unstable angina pectoris Cases of old myocardial infarction history) PTCA before and after their own comparative analysis. Results: Among 160 myocardial segments of 20 patients, the abnormal imaging of resting imaging was 196 (1 in 33 segments, 2 in 20 segments, 3 in 41 segments): nitroglycerin interventional imaging and PTCA The postoperative resting imaging abnormalities scores were significantly lower than the preoperative rest imaging and the scores of the two methods were similar, which were 104 and 97 respectively. While the normal segment of radionuclide increased by 46.7% and 67.9%, respectively, with 53 myocardial segments increased by 77.9%, which were similar to each other (P> 0.05) Significant difference (P <0.01). Preoperative ejection fraction was 44.5 ± 12.6%, postoperative 56.4 ± 16.3%, an increase of 26.8%. Conclusion: It is a simple, noninvasive and objective method to evaluate the myocardial viability of the myocardial nitroglycerin interventional myocardial perfusion imaging. It provides a powerful tool for preoperative selection of PTCA and evaluation of the curative effect after operation