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AIM:To investigate and review the contrast-enhanced multiple-phase computed tomography(CEMP CT)and magnetic resonance imaging(MRI)findings in patients with pathologically confirmed hepatic epithelioid hemangioendothelioma(HEHE).METHODS:Findings from imaging examinations in 8 patients(5 women and 3 men)with pathologically confirmed HEHE were retrospectively reviewed(CT images obtained from 7 patients and MR images obtained from 6 patients).The age of presentation varied from 27 years to 60 years(average age 39.8 years).RESULTS:There were two types of HEHE:multifocal type(n=7)and diffuse type(n=1).In the multifocal-type cases,there were 74 lesions on CT and 28 lesions on MRI with 7 lesions found with diffusion weighted imaging;18(24.3%)of 74 lesions on plainCT and 26(92.9%)of 28 lesions on pre-contrast MRI showed the target sign.On CEMP CT,28(37.8%) of 74 lesions appeared with the target sign and a progressive-enhancement rim and 9(12.2%)of 74 lesions displayed progressive enhancement,maintaining a state of persistent enhancement.On CEMP MRI,27(96.4%)of 28 lesions appeared with the target sign with a progressive-enhancement rim and 28(100%) of 28 lesions displayed progressive-enhancement,maintaining a state of persistent enhancement.In the diffuse-type cases,an enlarged liver was observed with a large nodule appearing with persistent enhancement on CEMP CT and MRI.CONCLUSION:The most important imaging features of HEHE are the target sign and/or progressive enhancement with persistent enhancement on CEMP CT and MRI.MRI is advantageous over CT in displaying these imaging features.
AIM: To investigate and review the contrast-enhanced multiple-phase computed tomography (CEMP CT) and magnetic resonance imaging (MRI) findings in patients with pathologically confirmed hepatic epithelioid hemangioendothelioma (HEHE). METHODS: Findings from imaging examinations in 8 patients women and 3 men) with pathologically confirmed HEHE were retrospectively reviewed (CT images obtained from 7 patients and MR images obtained from 6 patients). The age of presentation varied from 27 years to 60 years (average age 39.8 years) .RESULTS: There were Two types of HEHE: multifocal type (n = 7) and diffuse type (n = 1) .In the multifocal-type cases, there were 74 lesions on CT and 28 lesions on MRI with 7 lesions found with diffusion weighted imaging; 18 ( 24.3%) of 74 lesions on plain CT and 26 (92.9%) of 28 lesions on pre-contrast MRI showed the target sign. On CEMP CT, 28 (37.8%) of 74 lesions appeared with the target sign and a progressive-enhancement rim and 9 (12.2%) of 74 lesions showed progressive enhancement, ma intaining a state of persistent enhancement. On CEMP MRI, 27 (96.4%) of 28 lesions appeared with the target sign with a progressive-enhancement rim and 28 (100%) of 28 lesions showed progressive-enhancement, maintaining a state of persistent enhancement .In the diffuse-type cases, an enlarged liver was observed with a large nodule appearing with persistent enhancement on CEMP CT and MRI. CONCLUSION: The most important imaging features of HEHE are the target sign and / or progressive enhancement with persistent enhancement on CEMP CT and MRI.MRI is advantaged over CT in displaying these imaging features.